To eliminate inter-interviewer variation, psychiatric evaluation and psychometric markers were tested by 1 psychiatrist and 1 psychologist to establish the severity of depression. A convenience age-matched sample of healthy women was also recruited. Exclusion criteria comprised history of substance abuse, personality disorders, and/or other major psychopathology than depression. Patients and controls were subsequently interviewed by phone by trained interviewers using the Hospital Anxiety and Depression Scale, as well as other psychosocial instruments described below. The literature corroborates phone interviews as valid and precise tools for psychological data collection.[22]
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It is still unclear if IL-10 is related to depression as there are conflicting reports in the literature with regard to human studies[48] and in animal models.[49] IL-10 imbalance does affect depressive behaviors.[50] In studies involving SLE patients it has been previously observed that heightened levels of IL-10 are likely correlated with depression and neuropsychiatric disorders.[51,52].
This concept has existed in human knowledge and literature for a long time. In the Greco-Roman tradition, warrior narratives reference the experience of moral injury (called miasma, or moral pollution and purification), describing it as the effect of a critical situation wherein a person with legitimate and recognized authority betrays what is right.2
My name is Kellene Diana and I used to struggle with anxiety and depression. Nobody understood or wanted to understand; in fact they called me names and passed judgment before they even knew what I was going through. It made me so afraid to speak up and speak out about it that it completely silenced me for years. For a very long time I was full of anxiety, depression, fear, anger, self-doubt, low self-esteem and alcohol. Everything was hurting me emotionally, mentally and physically!
People living with depression are less likely to stick to the physical therapy or exercise routines that are important to their heart health. Depression also is associated with poor eating habits, smoking, overuse of alcohol and other habits that can also be detrimental to your heart. 2ff7e9595c
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